Research › Bio-DNA Cellular Marine Complex
Bio-DNA Cellular Marine Complex
The primary marine active in the formula, obtained from species living in deep, cold, pollution-free ocean waters off the coast of France. It carries the broadest research base of the three marine actives, and it is the component the Tufts University study was conducted on.
Per capsule
Cold extraction
and herring
Marine source
Parts per 100 mg of actives
What Has Been Studied
Four areas, across published and internal research.
Serum markers measured before and after twelve weeks
Researchers at Tufts University, working with two clinics in Spain, measured serum TNF and Substance P in 87 participants across twelve weeks. Both markers were significantly elevated at baseline against the control group, and both had decreased significantly by week twelve. Participants reported improvement in functioning, fatigue and general wellbeing from week four onward. The study was open label, without a placebo control.
Tsilioni, Pipis, Cabrera Freitag, Carrillo Izquierdo, Freitag and Theoharides. Journal of Clinical Therapeutics, August 2019. PubMed 31303280.
Reported a noticeable improvement in physical performance
A study of 2,960 participants with joint discomfort, average age 61, taking 400 mg per day of the marine complex alongside a vitamin B and E complex over 30 days. Nearly 84 percent reported a noticeable improvement in physical performance across the period.
Outcomes were self-reported and the study did not use a placebo control, so the figures below describe what participants said rather than a measured physiological change.
Reported substantially reduced discomfort against baseline
Reported partial relief
Reported total relief
Bio-DNA Cellular Marine Complex joint research. Internal study, not peer reviewed.
Self reported outcomes. The study did not use a placebo control.
Recorded an improvement in recuperation after exercise
Stamina was measured as oxygen consumption during exercise. Average consumption in participants was 38.3 millilitres per minute per kilogram at day zero, and rose over 21 days of the marine complex against placebo. In a related study, 80 percent of participants recorded an improvement in recuperation after exercise.
Protein contributes to the maintenance of muscle mass and to a growth in muscle mass.
Bio-DNA Cellular Marine Complex athletic performance research.
Oxygen consumption during exercise, measured against placebo.
Inhibition of lipid peroxidation in combination with vitamin E
A laboratory study of lipid peroxidation in iron-overloaded hepatocytes. Vitamin E at 250 mm combined with the marine complex at 4 mg per millilitre inhibited lipid peroxidation by more than 90 percent, a stronger result than either agent alone.
Lipid peroxidation is one of the ways free radicals damage cell structures. This is cell culture work rather than a study in people, and is reported here as such.
Bio-DNA Cellular Marine Complex antioxidant research.
Dose response for each agent alone, and for the two combined.
Reported reduction in mental fatigue at 15 days
A study of 688 participants, average age 44, taking 800 mg per day over 15 days. Participants self-reported changes across several measures, including a 54 percent reduction in mental fatigue and a 47 percent improvement in sleep. A separate study recorded reported reductions in fatigue both in the evening and on waking.
Self-reported outcomes without a placebo control.
Bio-DNA Cellular Marine Complex wellbeing research. Internal study, not peer reviewed.
Authorised statements relevant to this ingredient
- Protein contributes to a growth in muscle mass
- Protein contributes to the maintenance of muscle mass
- Protein contributes to the maintenance of normal bones
In Context
How the three actives divide the work.
230 mg per capsule
Peptide E Collagen
Marine collagen and elastin peptides. Studied for skin structure and the appearance of lines and wrinkles.
40 mg per capsule
Hydro MN Peptide
Marine cartilage extract, 35 to 40 percent chondroitin sulphate. Studied for skin structure under UV exposure and for glycaemic response.
A note on evidence
Two of the studies above are peer reviewed and indexed. The remainder are internal studies or laboratory work, and are labelled as such wherever they appear. They are included because they are part of the record, not because they carry the same weight.
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The rest of the record.
Every study on the formula, grouped by what it measured, with journals and identifiers.